A Human Genome Has Finally been fully decoded
A dormant pair of disseminated breast tumor cells in the brain (left). Note the astrocytes in cyan (blue/green) bordering the disseminated tumor cell-associated blood vessels (red). It turns out that reflects a functional, tumor-suppressive role. In the center image, you see the the same model, this time with a brain metastasis. Here you can note the astrocytes in cyan again are stripped from the blood vessels (red) within the metastasis and clustered at the edges. The final image (at right) is an intravital image of a brain metastasis (within a live mouse) with associated blood vessels perfused with a red, fluorescent chemical to allow them to be visualized.
Photos courtesy of Ghajar Lab, Fred Hutchinson Cancer Research Center
Understanding the mechanics of breast cancer metastasis
Why do some dormant cells wake up and start growing tumors in our brains or other organs while other dormant cells stay quiet? Why is the tissue in our lungs friendly to cancer proliferation while other tissue, like that in our muscles, is hostile to metastatic disease?
New work from Fred Hutch’s Ghajar Lab provides intriguing answers
First Artificial Kidney That Would Free People From Dialysis and Transplants Runs on Blood Pressure
The Kidney Project’s implantable bioartificial kidney, one that promises to free kidney disease patients from dialysis machines and transplant waiting lists, took another big step toward becoming reality—earning a $650,000 prize from KidneyX for its first-ever demonstration of a functional prototype of its implantable artificial kidney.